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C1GALT1 predicts poor prognosis and is a potential therapeutic target in head and neck cancer

Core 1 β1,3-galactosyltransferase (C1GALT1) controls the crucial step of GalNAc-type O-glycosylation and is overexpressed in various human malignancies. However, its role in head and neck squamous cell carcinoma (HNSCC) remains unclear. Here we demonstrate that C1GALT1 expression is upregulated in H...

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Detalles Bibliográficos
Autores principales: Lin, Mei-Chun, Chien, Pin-Hui, Wu, Hsin-Yi, Chen, Syue-Ting, Juan, Hsueh-Fen, Lou, Pei-Jen, Huang, Min-Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202324/
https://www.ncbi.nlm.nih.gov/pubmed/29930379
http://dx.doi.org/10.1038/s41388-018-0375-0