Activated hepatic stellate cells promote epithelial-to-mesenchymal transition in hepatocellular carcinoma through transglutaminase 2-induced pseudohypoxia

Activation of hepatic stellate cells reportedly contributes to progression of hepatocellular carcinoma (HCC). Herein, we use quantitative proteomics and ingenuity pathway analysis to show that transglutaminase 2 (TGM2) is upregulated in the course of activated hepatic stellate cells promoting epithe...

Descripción completa

Detalles Bibliográficos
Autores principales: Ma, Hui, Xie, Liqi, Zhang, Lan, Yin, Xin, Jiang, Hucong, Xie, Xiaoying, Chen, Rongxin, Lu, Haojie, Ren, Zhenggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202353/
https://www.ncbi.nlm.nih.gov/pubmed/30393774
http://dx.doi.org/10.1038/s42003-018-0177-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202353/
https://www.ncbi.nlm.nih.gov/pubmed/30393774
http://dx.doi.org/10.1038/s42003-018-0177-5

Ejemplares similares