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Activated hepatic stellate cells promote epithelial-to-mesenchymal transition in hepatocellular carcinoma through transglutaminase 2-induced pseudohypoxia
Activation of hepatic stellate cells reportedly contributes to progression of hepatocellular carcinoma (HCC). Herein, we use quantitative proteomics and ingenuity pathway analysis to show that transglutaminase 2 (TGM2) is upregulated in the course of activated hepatic stellate cells promoting epithe...
Autores principales: | Ma, Hui, Xie, Liqi, Zhang, Lan, Yin, Xin, Jiang, Hucong, Xie, Xiaoying, Chen, Rongxin, Lu, Haojie, Ren, Zhenggang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202353/ https://www.ncbi.nlm.nih.gov/pubmed/30393774 http://dx.doi.org/10.1038/s42003-018-0177-5 |
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