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Mesopontine cholinergic inputs to midbrain dopamine neurons drive stress-induced depressive-like behaviors

Stressful life events are primary environmental factors that markedly contribute to depression by triggering brain cellular maladaptations. Dysregulation of ventral tegmental area (VTA) dopamine neurons has been causally linked to the appearance of social withdrawal and anhedonia, two classical mani...

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Detalles Bibliográficos
Autores principales: Fernandez, Sebastian P., Broussot, Loïc, Marti, Fabio, Contesse, Thomas, Mouska, Xavier, Soiza-Reilly, Mariano, Marie, Hélène, Faure, Philippe, Barik, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202358/
https://www.ncbi.nlm.nih.gov/pubmed/30361503
http://dx.doi.org/10.1038/s41467-018-06809-7