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Previous antiretroviral drug use compromises standard first-line HIV therapy and is mediated through drug-resistance

In ART programs in sub-Saharan Africa, a growing proportion of HIV-infected persons initiating first-line antiretroviral therapy (ART) have a history of prior antiretroviral drug use (PAU). We assessed the effect of PAU on the risk of pre-treatment drug resistance (PDR) and virological failure (VF)...

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Detalles Bibliográficos
Autores principales: Inzaule, Seth C., Kityo, Cissy M., Siwale, Margaret, Akanmu, Alani Sulaimon, Wellington, Maureen, de Jager, Marleen, Ive, Prudence, Mandaliya, Kishor, Stevens, Wendy, Boender, T. Sonia, Ondoa, Pascale, Sigaloff, Kim C. E., Naniche, Denise, Rinke de Wit, Tobias F., Hamers, Raph L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202366/
https://www.ncbi.nlm.nih.gov/pubmed/30361640
http://dx.doi.org/10.1038/s41598-018-33538-0