Cargando…

Probing of G-Quadruplex Structures via Ligand-Sensitized Photochemical Reactions in (Br)U-Substituted DNA

We studied photochemical reactions of (Br)U-substituted G-quadruplex (G4) DNA substrates with two pyrene-substituted polyazamacrocyclic ligands, M-1PY and M-2PY. Both ligands bind to and stabilize G4-DNA structures without altering their folding topology, as demonstrated by FRET-melting experiments,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Saha, Abhijit, Bombard, Sophie, Granzhan, Anton, Teulade-Fichou, Marie-Paule
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202380/ https://www.ncbi.nlm.nih.gov/pubmed/30361545 http://dx.doi.org/10.1038/s41598-018-34141-z

Ejemplares similares

Identification of optimal fluorescent probes for G-quadruplex nucleic acids through systematic exploration of mono- and distyryl dye libraries
por: Xie, Xiao, et al.
Publicado: (2019)

“One Ring to Bind Them All”—Part II: Identification of Promising G-Quadruplex Ligands by Screening of Cyclophane-Type Macrocycles
por: Granzhan, Anton, et al.
Publicado: (2010)

BrdU immuno-tagged G-quadruplex ligands: a new ligand-guided immunofluorescence approach for tracking G-quadruplexes in cells
por: Masson, Thibaut, et al.
Publicado: (2021)

“One Ring to Bind Them All”—Part I: The Efficiency of the Macrocyclic Scaffold for G-Quadruplex DNA Recognition
por: Monchaud, David, et al.
Publicado: (2010)

TWJ-Screen: an isothermal screening assay to assess ligand/DNA junction interactions in vitro
por: Guyon, Ludivine, et al.
Publicado: (2018)

Thermodynamic fingerprints of ligand binding to human telomeric G-quadruplexes
por: Bončina, Matjaž, et al.
Publicado: (2015)

Oxadiazole/Pyridine-Based Ligands: A Structural Tuning for Enhancing G-Quadruplex Binding
por: Doria, Filippo, et al.
Publicado: (2018)

Selective recognition of pyrimidine–pyrimidine DNA mismatches by distance-constrained macrocyclic bis-intercalators
por: Bahr, Matthias, et al.
Publicado: (2008)

Double threading through DNA: NMR structural study of a bis-naphthalene macrocycle bound to a thymine–thymine mismatch
por: Jourdan, Muriel, et al.
Publicado: (2012)

Selectivity of Terpyridine Platinum Anticancer Drugs for G-quadruplex DNA
por: Morel, Elodie, et al.
Publicado: (2019)

Phen‐DC(3) Induces Refolding of Human Telomeric DNA into a Chair‐Type Antiparallel G‐Quadruplex through Ligand Intercalation
por: Ghosh, Anirban, et al.
Publicado: (2022)

Stimulation of ribosomal frameshifting by RNA G-quadruplex structures
por: Yu, Chien-Hung, et al.
Publicado: (2014)

The different activities of RNA G-quadruplex structures are controlled by flanking sequences
por: Zheng, Alice J-L, et al.
Publicado: (2021)

The human mitochondrial transcription factor A is a versatile G-quadruplex binding protein
por: Lyonnais, Sébastien, et al.
Publicado: (2017)

Alternative splicing of BCL-x is controlled by RBM25 binding to a G-quadruplex in BCL-x pre-mRNA
por: Le Sénéchal, Ronan, et al.
Publicado: (2023)

Corrigendum: The human mitochondrial transcription factor A is a versatile G-quadruplex binding protein
por: Lyonnais, Sébastien, et al.
Publicado: (2017)

SARS-CoV-2 Nsp3 unique domain SUD interacts with guanine quadruplexes and G4-ligands inhibit this interaction
por: Lavigne, Marc, et al.
Publicado: (2021)

Bisquinolinium compounds induce quadruplex-specific transcriptome changes in HeLa S3 cell lines
por: Halder, Rashi, et al.
Publicado: (2012)

Thermodynamically stable and genetically unstable G-quadruplexes are depleted in genomes across species
por: Puig Lombardi, Emilia, et al.
Publicado: (2019)

In Cellulo Protein-mRNA Interaction Assay to Determine the Action of G-Quadruplex-Binding Molecules
por: Prado Martins, Rodrigo, et al.
Publicado: (2018)

Genetic instability triggered by G-quadruplex interacting Phen-DC compounds in Saccharomyces cerevisiae
por: Piazza, Aurèle, et al.
Publicado: (2010)

Sneaking Out for Happy Hour: Yeast-Based Approaches to Explore and Modulate Immune Response and Immune Evasion
por: Angrand, Gaëlle, et al.
Publicado: (2019)

Platinum Complexes Can Bind to Telomeres by Coordination
por: Saker, Lina, et al.
Publicado: (2018)

Putative DNA G-quadruplex formation within the promoters of Plasmodium falciparum var genes
por: Smargiasso, Nicolas, et al.
Publicado: (2009)

A G-quadruplex structure within the 5′-UTR of TRF2 mRNA represses translation in human cells
por: Gomez, Dennis, et al.
Publicado: (2010)

Optimization of G‐Quadruplex Ligands through a SAR Study Combining Parallel Synthesis and Screening of Cationic Bis(acylhydrazones)
por: Reznichenko, Oksana, et al.
Publicado: (2022)

Identification of human telomerase assembly inhibitors enabled by a novel method to produce hTERT
por: Kellermann, Guillaume, et al.
Publicado: (2015)

Author Correction: Involvement of G-quadruplex regions in mammalian replication origin activity
por: Prorok, Paulina, et al.
Publicado: (2020)

hnRNP A1-mediated translational regulation of the G quadruplex-containing RON receptor tyrosine kinase mRNA linked to tumor progression
por: Cammas, Anne, et al.
Publicado: (2016)

Highly efficient radiosensitization of human glioblastoma and lung cancer cells by a G-quadruplex DNA binding compound
por: Merle, Patrick, et al.
Publicado: (2015)

Nucleolin directly mediates Epstein-Barr virus immune evasion through binding to G-quadruplexes of EBNA1 mRNA
por: Lista, María José, et al.
Publicado: (2017)

Triphenylamines Induce Cell Death Upon 2-Photon Excitation
por: Chennoufi, Rahima, et al.
Publicado: (2017)

THE PHOTOCHEMICAL REACTION IN PHOTOSYNTHESIS
por: Emerson, Robert, et al.
Publicado: (1932)

Ab initio investigation of Br-3d core-excited states in HBr and HBr(+) toward XUV probing of photochemical dynamics
por: Kobayashi, Yuki, et al.
Publicado: (2019)

Unprecedented reactivity of polyamines with aldehydic DNA modifications: structural determinants of reactivity, characterization and enzymatic stability of adducts
por: Gusti Ngurah Putu, Eka Putra, et al.
Publicado: (2023)

Substituted Dibenzodiazocines: Rapid Synthesis and Photochemical Properties
por: Klockmann, Felix, et al.
Publicado: (2021)

Photochemical Reactions in Dialdehyde Starch
por: Ziegler-Borowska, Marta, et al.
Publicado: (2018)

G-Quadruplexes and Their Ligands: Biophysical Methods to Unravel G-Quadruplex/Ligand Interactions
por: Santos, Tiago, et al.
Publicado: (2021)

Insights from Binding on Quadruplex Selective Carbazole Ligands
por: Müller, Diana, et al.
Publicado: (2021)

A mechanism for the extension and unfolding of parallel telomeric G-quadruplexes by human telomerase at single-molecule resolution
por: Paudel, Bishnu P, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_9dcoanois3ut2b4knvjpi1bj1f