Sublethal UV irradiation induces squamous differentiation via a p53-independent, DNA damage-mitosis checkpoint

The epidermis is a self-renewal epithelium continuously exposed to the genotoxic effects of ultraviolet (UV) light, the main cause of skin cancer. Therefore, it needs robust self-protective mechanisms facing genomic damage. p53 has been shown to mediate apoptosis in sunburn cells of the epidermis. H...

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Detalles Bibliográficos
Autores principales: de Pedro, Isabel, Alonso-Lecue, Pilar, Sanz-Gómez, Natalia, Freije, Ana, Gandarillas, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202398/
https://www.ncbi.nlm.nih.gov/pubmed/30361544
http://dx.doi.org/10.1038/s41419-018-1130-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202398/
https://www.ncbi.nlm.nih.gov/pubmed/30361544
http://dx.doi.org/10.1038/s41419-018-1130-8

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