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Fibroblast gene expression following asthmatic bronchial epithelial cell conditioning correlates with epithelial donor lung function and exacerbation history

Airway remodeling may contribute to decreased lung function in asthmatic children. Bronchial epithelial cells (BECs) may regulate fibroblast expression of extracellular matrix (ECM) constituents and fibroblast-to-myofibroblast transition (FMT). Our objective was to determine if human lung fibroblast...

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Detalles Bibliográficos
Autores principales: Reeves, Stephen R., Barrow, Kaitlyn A., Kolstad, Tessa K., White, Maria P., Rich, Lucille M., Wight, Thomas N., Debley, Jason S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202408/
https://www.ncbi.nlm.nih.gov/pubmed/30361541
http://dx.doi.org/10.1038/s41598-018-34021-6