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A Partial Differential Equation Approach to Inhalation Physiologically Based Pharmacokinetic Modeling
The heterogeneous nature of the lungs and the range of processes affecting pulmonary drug disposition make prediction of inhaled drugs challenging. These predictions are critical, as the local exposure cannot be measured and current inhalation physiologically based pharmacokinetic (PBPK) models do n...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202470/ https://www.ncbi.nlm.nih.gov/pubmed/30084547 http://dx.doi.org/10.1002/psp4.12344 |