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EMT induced by loss of LKB1 promotes migration and invasion of liver cancer cells through ZEB1-induced YAP signaling

Liver cancer cells often exhibit mesenchymal phenotypes, a critical phenotypic alteration of cancer cells termed the epithelial-mesenchymal transition (EMT). To examine whether liver kinase B1 (LKB1) serves a potential role in EMT in liver carcinogenesis, in the present study, it was determined that...

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Detalles Bibliográficos
Autores principales: Qiu, Bijun, Wei, Wei, Zhu, Jianwen, Fu, Guangshun, Lu, Dahai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202531/
https://www.ncbi.nlm.nih.gov/pubmed/30405784
http://dx.doi.org/10.3892/ol.2018.9445