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Green Tea Catechin Dramatically Promotes RNAi Mediated by Low-Molecular-Weight Polymers

[Image: see text] Cytosolic delivery is the major challenge that limits the clinical translation of siRNA-based therapeutics. Although thousands of polymers have been developed for siRNA delivery, the efficiency–toxicity correlation is unsatisfactory. Here, we report a facile strategy to fabricate c...

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Detalles Bibliográficos
Autores principales: Shen, Wanwan, Wang, Qingwei, Shen, Yang, Gao, Xiao, Li, Lei, Yan, Yang, Wang, Hui, Cheng, Yiyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202644/
https://www.ncbi.nlm.nih.gov/pubmed/30410970
http://dx.doi.org/10.1021/acscentsci.8b00363