Quantifying and reducing spurious alignments for the analysis of ultra-short ancient DNA sequences

BACKGROUND: The study of ancient DNA is hampered by degradation, resulting in short DNA fragments. Advances in laboratory methods have made it possible to retrieve short DNA fragments, thereby improving access to DNA preserved in highly degraded, ancient material. However, such material contains lar...

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Detalles Bibliográficos
Autores principales: de Filippo, Cesare, Meyer, Matthias, Prüfer, Kay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202837/
https://www.ncbi.nlm.nih.gov/pubmed/30359256
http://dx.doi.org/10.1186/s12915-018-0581-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202837/
https://www.ncbi.nlm.nih.gov/pubmed/30359256
http://dx.doi.org/10.1186/s12915-018-0581-9

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