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Quantifying and reducing spurious alignments for the analysis of ultra-short ancient DNA sequences
BACKGROUND: The study of ancient DNA is hampered by degradation, resulting in short DNA fragments. Advances in laboratory methods have made it possible to retrieve short DNA fragments, thereby improving access to DNA preserved in highly degraded, ancient material. However, such material contains lar...
Autores principales: | de Filippo, Cesare, Meyer, Matthias, Prüfer, Kay |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202837/ https://www.ncbi.nlm.nih.gov/pubmed/30359256 http://dx.doi.org/10.1186/s12915-018-0581-9 |
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