The manner of decay of genetically defective EYS gene transcripts in photoreceptor-directed fibroblasts derived from retinitis pigmentosa patients depends on the type of mutation

BACKGROUND: Generation of induced photoreceptors holds promise for in vitro modeling of intractable retinal diseases. Retinitis pigmentosa is an inherited retinal dystrophy that leads to visual impairment. The EYS gene was reported to be the most common gene responsible for autosomal recessive retin...

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Detalles Bibliográficos
Autores principales: Seko, Yuko, Iwanami, Masaki, Miyamoto-Matsui, Kiyoko, Takita, Shimpei, Aoi, Noriyuki, Umezawa, Akihiro, Kato, Seishi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202841/
https://www.ncbi.nlm.nih.gov/pubmed/30359287
http://dx.doi.org/10.1186/s13287-018-1016-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202841/
https://www.ncbi.nlm.nih.gov/pubmed/30359287
http://dx.doi.org/10.1186/s13287-018-1016-9

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