TMEM126B deficiency reduces mitochondrial SDH oxidation by LPS, attenuating HIF-1α stabilization and IL-1β expression

Mitochondrial derived reactive oxygen species (mtROS) are known for their signaling qualities in both physiology and pathology. To elucidate mitochondrial complex I-dependent ROS-signaling after lipopolysaccharide (LPS)-stimulation THP-1 macrophages with a knockdown of the transmembrane protein TMEM...

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Detalles Bibliográficos
Autores principales: Fuhrmann, Dominik C., Wittig, Ilka, Brüne, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202876/
https://www.ncbi.nlm.nih.gov/pubmed/30368040
http://dx.doi.org/10.1016/j.redox.2018.10.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202876/
https://www.ncbi.nlm.nih.gov/pubmed/30368040
http://dx.doi.org/10.1016/j.redox.2018.10.007

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