Nitric oxide contributes to protein homeostasis by S-nitrosylations of the chaperone HSPA8 and the ubiquitin ligase UBE2D

Upregulations of neuronal nitric oxide synthase (nNOS) in the rodent brain have been associated with neuronal aging. To address underlying mechanisms we generated SH-SY5Y neuronal cells constitutively expressing nNOS at a level similar to mouse brain (nNOS+ versus MOCK). Initial experiments revealed...

Descripción completa

Detalles Bibliográficos
Autores principales: Valek, Lucie, Heidler, Juliana, Scheving, Reynir, Wittig, Ilka, Tegeder, Irmgard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202877/
https://www.ncbi.nlm.nih.gov/pubmed/30368041
http://dx.doi.org/10.1016/j.redox.2018.10.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202877/
https://www.ncbi.nlm.nih.gov/pubmed/30368041
http://dx.doi.org/10.1016/j.redox.2018.10.002

Ejemplares similares