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Study investigating the generalisability of a COPD trial based in primary care (Salford Lung Study) and the presence of a Hawthorne effect

INTRODUCTION: Traditional phase IIIb randomised trials may not reflect routine clinical practice. The Salford Lung Study in chronic obstructive pulmonary disease (SLS COPD) allowed broad inclusion criteria and followed patients in routine practice. We assessed whether SLS COPD approximated the Engla...

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Detalles Bibliográficos
Autores principales: Pate, Alexander, Barrowman, Michael, Webb, David, Pimenta, Jeanne M, Davis, Kourtney J, Williams, Rachael, Van Staa, Tjeerd, Sperrin, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203022/
https://www.ncbi.nlm.nih.gov/pubmed/30397486
http://dx.doi.org/10.1136/bmjresp-2018-000339