Lentivirus-mediated siRNA knockdown of SPHK1 inhibits proliferation and tumorigenesis of neuroblastoma

BACKGROUND: The overexpression of sphingosine kinase 1 (SPHK1) is responsible for the progress of many cancers. However, the role of SPHK1 in the development and progression of neuroblastoma (NB) remain largely unknown. Here in this study, we explored whether silencing SPHK1 by lentivirus-mediated s...

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Detalles Bibliográficos
Autores principales: Su, Lin, Tian, Junyan, Sun, Jinsong, Han, Nuan, Feng, Lin, Yu, Baohua, Wang, Yuepeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203087/
https://www.ncbi.nlm.nih.gov/pubmed/30425511
http://dx.doi.org/10.2147/OTT.S180962

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203087/
https://www.ncbi.nlm.nih.gov/pubmed/30425511
http://dx.doi.org/10.2147/OTT.S180962

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