TNFα promotes glioblastoma A172 cell mitochondrial apoptosis via augmenting mitochondrial fission and repression of MAPK–ERK–YAP signaling pathways

BACKGROUND AND OBJECTIVE: The present study was designed to explore the roles of mitochondrial fission and MAPK–ERK–YAP signaling pathways and to determine their mutual relationship in TNFα-mediated glioblastoma mitochondrial apoptosis. MATERIALS AND METHODS: Cellular viability was measured via TUNE...

Descripción completa

Detalles Bibliográficos
Autores principales: Lu, Changyu, Chen, Xiaolei, Wang, Qun, Xu, Xinghua, Xu, Bainan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203110/
https://www.ncbi.nlm.nih.gov/pubmed/30425514
http://dx.doi.org/10.2147/OTT.S184337

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203110/
https://www.ncbi.nlm.nih.gov/pubmed/30425514
http://dx.doi.org/10.2147/OTT.S184337

Ejemplares similares