Safety, tolerability, and pharmacokinetics of single and repeat ascending doses of CHF6001, a novel inhaled phosphodiesterase-4 inhibitor: two randomized trials in healthy volunteers

PURPOSE: The purpose of this study was to evaluate safety, tolerability, and pharmacokinetics (PK) of CHF6001, an inhaled phosphodiesterase-4 inhibitor. MATERIALS AND METHODS: Two healthy volunteer, randomized, double-blind, placebo-controlled studies were conducted. In each, Part 1 evaluated single...

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Detalles Bibliográficos
Autores principales: Mariotti, Fabrizia, Govoni, Mirco, Lucci, Germano, Santoro, Debora, Nandeuil, Marie Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203112/
https://www.ncbi.nlm.nih.gov/pubmed/30425469
http://dx.doi.org/10.2147/COPD.S174156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203112/
https://www.ncbi.nlm.nih.gov/pubmed/30425469
http://dx.doi.org/10.2147/COPD.S174156

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