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Mst1 regulates non-small cell lung cancer A549 cell apoptosis by inducing mitochondrial damage via ROCK1/F-actin pathways

Mammalian STE20-like kinase 1 (Mst1) is well recognized as a major tumor suppressor in cancer development, growth, metabolic reprogramming, metastasis, cell death and recurrence. However, the roles of Mst1 in non-small cell lung cancer (NSCLC) A549 cell phenotypic alterations remain to be elucidated...

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Detalles Bibliográficos
Autores principales: Zhang, Weiqiang, Liu, Keiqiang, Pei, Yingxin, Ma, Jingbo, Tan, Jiang, Zhao, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203146/
https://www.ncbi.nlm.nih.gov/pubmed/30320378
http://dx.doi.org/10.3892/ijo.2018.4586