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Downregulation of microRNA-4295 enhances cisplatin-induced gastric cancer cell apoptosis through the EGFR/PI3K/Akt signaling pathway by targeting LRIG1

Gastric cancer (GC) is one of the leading causes of cancer-associated mortality worldwide. The aim of the present study was to investigate the mechanism of microRNA-4295 (miR-4295), which regulates cisplatin (DDP)-induced apoptosis in GC cells through the leucinerich repeats and immunoglobulin-like...

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Detalles Bibliográficos
Autores principales: Yan, Rong, Li, Kang, Yuan, Da-Wei, Wang, Hao-Nan, Zhang, Yong, Dang, Cheng-Xue, Zhu, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203147/
https://www.ncbi.nlm.nih.gov/pubmed/30320337
http://dx.doi.org/10.3892/ijo.2018.4595