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Inhibition of BRD4 suppresses tumor growth in prostate cancer via the enhancement of FOXO1 expression

Prostate cancer (PCa) is a malignant tumor with a high incidence in males. Localized tumors can be treated via surgery or radiation; however, it remains difficult to prevent disease progression. Bromodomain-containing protein 4 (BRD4) is an epigenetic reader protein that binds to acetylated lysine o...

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Detalles Bibliográficos
Autores principales: Tan, Yifan, Wang, Lei, Du, Yang, Liu, Xiuheng, Chen, Zhiyuan, Weng, Xiaodong, Guo, Jia, Chen, Hui, Wang, Min, Wang, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203153/
https://www.ncbi.nlm.nih.gov/pubmed/30272279
http://dx.doi.org/10.3892/ijo.2018.4577