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Inhibition of BRD4 suppresses tumor growth in prostate cancer via the enhancement of FOXO1 expression
Prostate cancer (PCa) is a malignant tumor with a high incidence in males. Localized tumors can be treated via surgery or radiation; however, it remains difficult to prevent disease progression. Bromodomain-containing protein 4 (BRD4) is an epigenetic reader protein that binds to acetylated lysine o...
Autores principales: | Tan, Yifan, Wang, Lei, Du, Yang, Liu, Xiuheng, Chen, Zhiyuan, Weng, Xiaodong, Guo, Jia, Chen, Hui, Wang, Min, Wang, Xiao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203153/ https://www.ncbi.nlm.nih.gov/pubmed/30272279 http://dx.doi.org/10.3892/ijo.2018.4577 |
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