Constriction of Retinal Venules to Endothelin-1: Obligatory Roles of ET(A) Receptors, Extracellular Calcium Entry, and Rho Kinase

PURPOSE: Endothelin-1 (ET-1) is a potent vasoconstrictor peptide implicated in retinal venous pathologies such as diabetic retinopathy and retinal vein occlusion. However, underlying mechanisms contributing to venular constriction remain unknown. Thus, we examined the roles of ET-1 receptors, extrac...

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Detalles Bibliográficos
Autores principales: Chen, Yen-Lin, Ren, Yi, Xu, Wenjuan, Rosa, Robert H., Kuo, Lih, Hein, Travis W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2018
Materias:
Physiology and Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203175/
https://www.ncbi.nlm.nih.gov/pubmed/30372743
http://dx.doi.org/10.1167/iovs.18-25369

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203175/
https://www.ncbi.nlm.nih.gov/pubmed/30372743
http://dx.doi.org/10.1167/iovs.18-25369

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