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Constriction of Retinal Venules to Endothelin-1: Obligatory Roles of ET(A) Receptors, Extracellular Calcium Entry, and Rho Kinase
PURPOSE: Endothelin-1 (ET-1) is a potent vasoconstrictor peptide implicated in retinal venous pathologies such as diabetic retinopathy and retinal vein occlusion. However, underlying mechanisms contributing to venular constriction remain unknown. Thus, we examined the roles of ET-1 receptors, extrac...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Association for Research in Vision and Ophthalmology
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203175/ https://www.ncbi.nlm.nih.gov/pubmed/30372743 http://dx.doi.org/10.1167/iovs.18-25369 |