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Physiological cyclic hydrostatic pressure induces osteogenic lineage commitment of human bone marrow stem cells: a systematic study

BACKGROUND: Physical loading is necessary to maintain bone tissue integrity. Loading-induced fluid shear is recognised as one of the most potent bone micromechanical cues and has been shown to direct stem cell osteogenesis. However, the effect of pressure transients, which drive fluid flow, on human...

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Detalles Bibliográficos
Autores principales: Stavenschi, Elena, Corrigan, Michele A., Johnson, Gillian P., Riffault, Mathieu, Hoey, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203194/
https://www.ncbi.nlm.nih.gov/pubmed/30359324
http://dx.doi.org/10.1186/s13287-018-1025-8