FBXO17 promotes cell proliferation through activation of Akt in lung adenocarcinoma cells

BACKGROUND: The ubiquitin-proteasome pathway, mediated in part, by ubiquitin E3 ligases, is critical in regulating cellular processes such as cell proliferation, apoptosis, and migration. FBXO17 was recently identified as an F-box protein that targets glycogen synthase kinase-3β to the E3 ubiquitin...

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Detalles Bibliográficos
Autores principales: Suber, Tomeka L., Nikolli, Ina, O’Brien, Michael E., Londino, James, Zhao, Jing, Chen, Kong, Mallampalli, Rama K., Zhao, Yutong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203195/
https://www.ncbi.nlm.nih.gov/pubmed/30359271
http://dx.doi.org/10.1186/s12931-018-0910-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203195/
https://www.ncbi.nlm.nih.gov/pubmed/30359271
http://dx.doi.org/10.1186/s12931-018-0910-0

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