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Structural and dynamic basis of substrate permissiveness in hydroxycinnamoyltransferase (HCT)

Substrate permissiveness has long been regarded as the raw materials for the evolution of new enzymatic functions. In land plants, hydroxycinnamoyltransferase (HCT) is an essential enzyme of the phenylpropanoid metabolism. Although essential enzymes are normally associated with high substrate specif...

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Detalles Bibliográficos
Autores principales: Chiang, Ying-Chih, Levsh, Olesya, Lam, Chun Kei, Weng, Jing-Ke, Wang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203249/
https://www.ncbi.nlm.nih.gov/pubmed/30365487
http://dx.doi.org/10.1371/journal.pcbi.1006511