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CD25 and TGF-β blockade based on predictive integrated immune ratio inhibits tumor growth in pancreatic cancer

BACKGROUND: The prognosis of pancreatic ductal adenocarcinoma (PDAC) remains poor due to the difficulty of disease diagnosis and therapy. Immunotherapy has had robust performance against several malignancies, including PDAC. In this study, we aim to analyze the expression of CD8 and FoxP3 on T lymph...

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Detalles Bibliográficos
Autores principales: Pu, Ning, Zhao, Guochao, Yin, Hanlin, Li, Jian-ang, Nuerxiati, Abulimiti, Wang, Dansong, Xu, Xuefeng, Kuang, Tiantao, Jin, Dayong, Lou, Wenhui, Wu, Wenchuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203282/
https://www.ncbi.nlm.nih.gov/pubmed/30359281
http://dx.doi.org/10.1186/s12967-018-1673-6