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Characterization of embryonic stem cell-differentiated fibroblasts as mesenchymal stem cells with robust expansion capacity and attenuated innate immunity

BACKGROUND: Mesenchymal stem cells (MSCs) isolated from adult tissues (Ad-MSCs) have shown great promise for use in regenerative medicine. However, their poor in vitro expansion capacity and tissue scarcity have been major limitations. In this study, we demonstrate that mouse embryonic stem cells (m...

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Detalles Bibliográficos
Autores principales: D’Angelo, William, Chen, Bohan, Gurung, Chandan, Guo, Yan-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203291/
https://www.ncbi.nlm.nih.gov/pubmed/30359317
http://dx.doi.org/10.1186/s13287-018-1033-8