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Strong G-Protein-Mediated Inhibition of Sodium Channels

Voltage-gated sodium channels (VGSCs) are strategically positioned to mediate neuronal plasticity because of their influence on action potential waveform. VGSC function may be strongly inhibited by local anesthetic and antiepileptic drugs and modestly modulated via second messenger pathways. Here, w...

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Detalles Bibliográficos
Autores principales: Mattheisen, Glynis B., Tsintsadze, Timur, Smith, Stephen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203318/
https://www.ncbi.nlm.nih.gov/pubmed/29847805
http://dx.doi.org/10.1016/j.celrep.2018.04.109