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Involvement of VNUT-exocytosis in transient receptor potential vanilloid 4-dependent ATP release from gastrointestinal epithelium
Adenosine triphosphate (ATP) modulates mechanosensitive vagal afferent nerves in the gastrointestinal tract. ATP is stored in secretory vesicles via the ATP transporter VNUT. Recently, the bisphosphate clodronate was reported to inhibit VNUT and was suggested to be a safe potent therapeutic option f...
Autores principales: | Mihara, Hiroshi, Uchida, Kunitoshi, Koizumi, Schuichi, Moriyama, Yoshinori |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203352/ https://www.ncbi.nlm.nih.gov/pubmed/30365528 http://dx.doi.org/10.1371/journal.pone.0206276 |
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