HJURP antagonizes CENP-A mislocalization driven by the H3.3 chaperones HIRA and DAXX

The centromere specific histone H3 variant CENP-A/CENH3 specifies where the kinetochore is formed in most eukaryotes. Despite tight regulation of CENP-A levels in normal cells, overexpression of CENP-A is a feature shared by various types of solid tumors and results in its mislocalization to non-cen...

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Detalles Bibliográficos
Autores principales: Nye, Jonathan, Sturgill, David, Athwal, Rajbir, Dalal, Yamini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203356/
https://www.ncbi.nlm.nih.gov/pubmed/30365520
http://dx.doi.org/10.1371/journal.pone.0205948

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203356/
https://www.ncbi.nlm.nih.gov/pubmed/30365520
http://dx.doi.org/10.1371/journal.pone.0205948

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