Cargando…

HJURP antagonizes CENP-A mislocalization driven by the H3.3 chaperones HIRA and DAXX

The centromere specific histone H3 variant CENP-A/CENH3 specifies where the kinetochore is formed in most eukaryotes. Despite tight regulation of CENP-A levels in normal cells, overexpression of CENP-A is a feature shared by various types of solid tumors and results in its mislocalization to non-cen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nye, Jonathan, Sturgill, David, Athwal, Rajbir, Dalal, Yamini
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203356/ https://www.ncbi.nlm.nih.gov/pubmed/30365520 http://dx.doi.org/10.1371/journal.pone.0205948

Ejemplares similares

Correction: HJURP antagonizes CENP-A mislocalization driven by the H3.3 chaperones HIRA and DAXX
Publicado: (2018)

H3.Y discriminates between HIRA and DAXX chaperone complexes and reveals unexpected insights into human DAXX-H3.3-H4 binding and deposition requirements
por: Zink, Lisa-Maria, et al.
Publicado: (2017)

CENP-B protects centromere chromatin integrity by facilitating histone deposition via the H3.3-specific chaperone Daxx
por: Morozov, Viacheslav M., et al.
Publicado: (2017)

Mechanism of centromere recruitment of the CENP-A chaperone HJURP and its implications for centromere licensing
por: Pan, Dongqing, et al.
Publicado: (2019)

Functional activity of the H3.3 histone chaperone complex HIRA requires trimerization of the HIRA subunit
por: Ray-Gallet, Dominique, et al.
Publicado: (2018)

Unraveling the Role of Histone Variant CENP-A and Chaperone HJURP Expression in Thymic Epithelial Neoplasms
por: Levidou, Georgia, et al.
Publicado: (2022)

The H3.3 chaperone Hira complex orchestrates oocyte developmental competence
por: Smith, Rowena, et al.
Publicado: (2022)

Xenopus HJURP and condensin II are required for CENP-A assembly
por: Bernad, Rafael, et al.
Publicado: (2011)

Xenopus HJURP and condensin II are required for CENP-A assembly
por: Bernad, Rafael, et al.
Publicado: (2011)

New players in heterochromatin silencing: histone variant H3.3 and the ATRX/DAXX chaperone
por: Voon, Hsiao P.J., et al.
Publicado: (2016)

The histone H3/H4 chaperone CHAF1B prevents the mislocalization of CENP-A for chromosomal stability
por: Shrestha, Roshan L., et al.
Publicado: (2023)

Ubinuclein-1 confers histone H3.3-specific-binding by the HIRA histone chaperone complex
por: Daniel Ricketts, M, et al.
Publicado: (2015)

The histone H3.3 chaperone HIRA restrains erythroid-biased differentiation of adult hematopoietic stem cells
por: Murdaugh, Rebecca L., et al.
Publicado: (2021)

CENP-A nucleosomes localize to transcription factor hotspots and subtelomeric sites in human cancer cells
por: Athwal, Rajbir K, et al.
Publicado: (2015)

Calcium-Dependent Dephosphorylation of the Histone Chaperone DAXX Regulates H3.3 Loading and Transcription upon Neuronal Activation
por: Michod, David, et al.
Publicado: (2012)

DAXX adds a de novo H3.3K9me3 deposition pathway to the histone chaperone network
por: Carraro, Massimo, et al.
Publicado: (2023)

HJURP interaction with the condensin II complex during G1 promotes CENP-A deposition
por: Barnhart-Dailey, Meghan C., et al.
Publicado: (2017)

Histone chaperone HIRA deposits histone H3.3 onto foreign viral DNA and contributes to anti-viral intrinsic immunity
por: Rai, Taranjit Singh, et al.
Publicado: (2017)

CENP-A nucleosome clusters form rosette-like structures around HJURP during G1
por: Andronov, Leonid, et al.
Publicado: (2019)

Repression of CENP-A assembly in metaphase requires HJURP phosphorylation and inhibition by M18BP1
por: Flores Servin, Julio C., et al.
Publicado: (2023)

TGF-β1 promotes expression of fibrosis-related genes through the induction of histone variant H3.3 and histone chaperone HIRA
por: Shindo, Toshihiro, et al.
Publicado: (2018)

Aberrant chromatin landscape following loss of the H3.3 chaperone Daxx in haematopoietic precursors leads to Pu.1-mediated neutrophilia and inflammation
por: Gerber, Julia P., et al.
Publicado: (2021)

Dbf4-Dependent Kinase (DDK)-Mediated Proteolysis of CENP-A Prevents Mislocalization of CENP-A in Saccharomyces cerevisiae
por: Eisenstatt, Jessica R., et al.
Publicado: (2020)

HJURP is a CENP-A chromatin assembly factor sufficient to form a functional de novo kinetochore
por: Barnhart, Meghan C., et al.
Publicado: (2011)

Mislocalization of centromeric histone H3 variant CENP-A contributes to chromosomal instability (CIN) in human cells
por: Shrestha, Roshan L., et al.
Publicado: (2017)

The histone chaperone function of Daxx is dispensable for embryonic development
por: Sun, Chang, et al.
Publicado: (2023)

Author Correction: Aberrant chromatin landscape following loss of the H3.3 chaperone Daxx in haematopoietic precursors leads to Pu.1-mediated neutrophilia and inflammation
por: Gerber, Julia P., et al.
Publicado: (2022)

Epigenetic engineering shows H3K4me2 is required for HJURP targeting and CENP-A assembly on a synthetic human kinetochore
por: Bergmann, Jan H, et al.
Publicado: (2011)

The HIRA complex that deposits the histone H3.3 is conserved in Arabidopsis and facilitates transcriptional dynamics
por: Nie, Xin, et al.
Publicado: (2014)

The impact of the HIRA histone chaperone upon global nucleosome architecture
por: Gal, Csenge, et al.
Publicado: (2015)

The Histone Chaperone HIRA Is a Positive Regulator of Seed Germination
por: Layat, Elodie, et al.
Publicado: (2021)

Morc3 silences endogenous retroviruses by enabling Daxx-mediated histone H3.3 incorporation
por: Groh, Sophia, et al.
Publicado: (2021)

A role for the histone chaperone DAXX in the structural organization of heterochromatin
por: Rapkin, Lindsy M, et al.
Publicado: (2013)

The histone chaperone DAXX maintains the structural organization of heterochromatin domains
por: Rapkin, Lindsy M., et al.
Publicado: (2015)

PTEN regulates glioblastoma oncogenesis through chromatin-associated complexes of DAXX and histone H3.3
por: Benitez, Jorge A., et al.
Publicado: (2017)

Histone chaperone HIRA complex regulates retrotransposons in embryonic stem cells
por: Zhang, Miao, et al.
Publicado: (2022)

DAXX co-folds with H3.3/H4 using high local stability conferred by the H3.3 variant recognition residues
por: DeNizio, Jamie E., et al.
Publicado: (2014)

CENP-A and H3 Nucleosomes Display a Similar Stability to Force-Mediated Disassembly
por: Kim, Sung Hyun, et al.
Publicado: (2016)

HJURP puts the centromere in place
por: Short, Ben
Publicado: (2011)

Drosophila Yemanuclein and HIRA Cooperate for De Novo Assembly of H3.3-Containing Nucleosomes in the Male Pronucleus
por: Orsi, Guillermo A., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_fjqckfbn2648rskpf33n5bth3e