CB1 receptor blockade ameliorates hepatic fat infiltration and inflammation and increases Nrf2-AMPK pathway in a rat model of severely uncontrolled diabetes

Previous studies have shown that the CB1 receptor antagonist reverses steatohepatitis and its related features of metabolic syndrome, such as obesity and type 2 diabetes. However, the beneficial effects of CB1 receptor blockade on hepatic steatosis and inflammation have not been investigated indepen...

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Detalles Bibliográficos
Autores principales: Chang, Eugene, Kim, Dae-Hee, Yang, Hyekyung, Lee, Da Hyun, Bae, Soo Han, Park, Cheol-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203369/
https://www.ncbi.nlm.nih.gov/pubmed/30365523
http://dx.doi.org/10.1371/journal.pone.0206152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203369/
https://www.ncbi.nlm.nih.gov/pubmed/30365523
http://dx.doi.org/10.1371/journal.pone.0206152

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