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CB1 receptor blockade ameliorates hepatic fat infiltration and inflammation and increases Nrf2-AMPK pathway in a rat model of severely uncontrolled diabetes
Previous studies have shown that the CB1 receptor antagonist reverses steatohepatitis and its related features of metabolic syndrome, such as obesity and type 2 diabetes. However, the beneficial effects of CB1 receptor blockade on hepatic steatosis and inflammation have not been investigated indepen...
Autores principales: | Chang, Eugene, Kim, Dae-Hee, Yang, Hyekyung, Lee, Da Hyun, Bae, Soo Han, Park, Cheol-Young |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203369/ https://www.ncbi.nlm.nih.gov/pubmed/30365523 http://dx.doi.org/10.1371/journal.pone.0206152 |
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