Central Dicer-miR-103/107 controls developmental switch of POMC progenitors into NPY neurons and impacts glucose homeostasis

Proopiomelanocortin (POMC) neurons are major negative regulators of energy balance. A distinct developmental property of POMC neurons is that they can adopt an orexigenic neuropeptide Y (NPY) phenotype. However, the mechanisms underlying the differentiation of Pomc progenitors remain unknown. Here,...

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Detalles Bibliográficos
Autores principales: Croizier, Sophie, Park, Soyoung, Maillard, Julien, Bouret, Sebastien G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203430/
https://www.ncbi.nlm.nih.gov/pubmed/30311908
http://dx.doi.org/10.7554/eLife.40429

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203430/
https://www.ncbi.nlm.nih.gov/pubmed/30311908
http://dx.doi.org/10.7554/eLife.40429

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