DNA repair protein Rad18 restricts LINE-1 mobility

Long interspersed element-1 (LINE-1, L1) is a mobile genetic element comprising about 17% of the human genome. L1 utilizes an endonuclease to insert L1 cDNA into the target genomic DNA, which induces double-strand DNA breaks in the human genome and activates the DNA damage signaling pathway, resulti...

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Detalles Bibliográficos
Autores principales: Ariumi, Yasuo, Kawano, Koudai, Yasuda-Inoue, Mariko, Kuroki, Misao, Fukuda, Hiroyuki, Siddiqui, Rokeya, Turelli, Priscilla, Tateishi, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203705/
https://www.ncbi.nlm.nih.gov/pubmed/30367120
http://dx.doi.org/10.1038/s41598-018-34288-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203705/
https://www.ncbi.nlm.nih.gov/pubmed/30367120
http://dx.doi.org/10.1038/s41598-018-34288-9

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