Dietary cholesterol promotes steatohepatitis related hepatocellular carcinoma through dysregulated metabolism and calcium signaling

The underlining mechanisms of dietary cholesterol and nonalcoholic steatohepatitis (NASH) in contributing to hepatocellular carcinoma (HCC) remain undefined. Here we demonstrated that high-fat-non-cholesterol-fed mice developed simple steatosis, whilst high-fat-high-cholesterol-fed mice developed NA...

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Detalles Bibliográficos
Autores principales: Liang, Jessie Qiaoyi, Teoh, Narcissus, Xu, Lixia, Pok, Sharon, Li, Xiangchun, Chu, Eagle S. H., Chiu, Jonathan, Dong, Ling, Arfianti, Evi, Haigh, W. Geoffrey, Yeh, Matthew M., Ioannou, George N., Sung, Joseph J. Y., Farrell, Geoffrey, Yu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203711/
https://www.ncbi.nlm.nih.gov/pubmed/30367044
http://dx.doi.org/10.1038/s41467-018-06931-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203711/
https://www.ncbi.nlm.nih.gov/pubmed/30367044
http://dx.doi.org/10.1038/s41467-018-06931-6

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