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IFITM3 inhibits virus-triggered induction of type I interferon by mediating autophagosome-dependent degradation of IRF3

Interferon-induced transmembrane protein 3 (IFITM3) is a restriction factor that can be induced by viral infection and interferons (IFNs). It inhibits the entry and replication of many viruses, which are independent of receptor usage but dependent on processes that occur in endosomes. In this study,...

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Detalles Bibliográficos
Autores principales: Jiang, Li-Qun, Xia, Tian, Hu, Yun-Hong, Sun, Ming-Shun, Yan, Shuang, Lei, Cao-Qi, Shu, Hong-Bing, Guo, Ji-Hua, Liu, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203713/
https://www.ncbi.nlm.nih.gov/pubmed/28435159
http://dx.doi.org/10.1038/cmi.2017.15