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Target-based therapeutic matching of phase I trials in patients with metastatic breast cancer in a tertiary referral centre
BACKGROUND: Greater understanding of the molecular classification of breast cancer has permitted the development of rational drug design strategies. In a phase I clinical trial setting, molecular profiling with next-generation sequencing of individual tumour samples has been employed to guide treatm...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203714/ https://www.ncbi.nlm.nih.gov/pubmed/30318518 http://dx.doi.org/10.1038/s41416-018-0290-8 |