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Target-based therapeutic matching of phase I trials in patients with metastatic breast cancer in a tertiary referral centre

BACKGROUND: Greater understanding of the molecular classification of breast cancer has permitted the development of rational drug design strategies. In a phase I clinical trial setting, molecular profiling with next-generation sequencing of individual tumour samples has been employed to guide treatm...

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Detalles Bibliográficos
Autores principales: O’Carrigan, Brent, Lim, Joline Si Jing, Jalil, Awais, Harris, Samuel John, Papadatos-Pastos, Dionysis, Banerji, Udai, Lopez, Juanita, de Bono, Johann Sebastian, Yap, Timothy Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203714/
https://www.ncbi.nlm.nih.gov/pubmed/30318518
http://dx.doi.org/10.1038/s41416-018-0290-8