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Colon-specific eQTL analysis to inform on functional SNPs

BACKGROUND: Genome-wide association studies on colorectal cancer have identified more than 60 susceptibility loci, but for most of them there is no clear knowledge of functionality or the underlying gene responsible for the risk modification. Expression quantitative trail loci (eQTL) may provide fun...

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Detalles Bibliográficos
Autores principales: Moreno, Victor, Alonso, M. Henar, Closa, Adrià, Vallés, Xavier, Diez-Villanueva, Anna, Valle, Laura, Castellví-Bel, Sergi, Sanz-Pamplona, Rebeca, Lopez-Doriga, Adriana, Cordero, David, Solé, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203735/
https://www.ncbi.nlm.nih.gov/pubmed/30283144
http://dx.doi.org/10.1038/s41416-018-0018-9