Mkk4 and Mkk7 are important for retinal development and axonal injury-induced retinal ganglion cell death

The mitogen-activated protein kinase (MAPK) pathway has been shown to be involved in both neurodevelopment and neurodegeneration. c-Jun N-terminal kinase (JNK), a MAPK important in retinal development and after optic nerve crush injury, is regulated by two upstream kinases: MKK4 and MKK7. The specif...

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Detalles Bibliográficos
Autores principales: Syc-Mazurek, Stephanie B., Rausch, Rebecca L., Fernandes, Kimberly A., Wilson, Michael P., Libby, Richard T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203745/
https://www.ncbi.nlm.nih.gov/pubmed/30367030
http://dx.doi.org/10.1038/s41419-018-1079-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203745/
https://www.ncbi.nlm.nih.gov/pubmed/30367030
http://dx.doi.org/10.1038/s41419-018-1079-7

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