Antiviral activity of the mineralocorticoid receptor NR3C2 against Herpes simplex virus Type 1 (HSV-1) infection

Analysis of a genome-scale RNA interference screen of host factors affecting herpes simplex virus type 1 (HSV-1) revealed that the mineralocorticoid receptor (MR) inhibits HSV-1 replication. As a ligand-activated transcription factor the MR regulates sodium transport and blood pressure in the kidney...

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Detalles Bibliográficos
Autores principales: Haas, Jürgen G., Weber, Julia, Gonzalez, Orland, Zimmer, Ralf, Griffiths, Samantha J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203759/
https://www.ncbi.nlm.nih.gov/pubmed/30367157
http://dx.doi.org/10.1038/s41598-018-34241-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203759/
https://www.ncbi.nlm.nih.gov/pubmed/30367157
http://dx.doi.org/10.1038/s41598-018-34241-w

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