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Mice deficient in the mitochondrial branched-chain aminotransferase (BCATm) respond with delayed tumour growth to a challenge with EL-4 lymphoma

BACKGROUND: The mitochondrial branched-chain aminotransferase (BCATm) is a recently discovered cancer marker with a poorly defined role in tumour progression. METHODS: To understand how a loss of function of BCATm affects cancer, the global knockout mouse BCATmKO was challenged with EL-4 lymphoma un...

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Detalles Bibliográficos
Autores principales: Ananieva, Elitsa A., Bostic, Joshua N., Torres, Ashley A., Glanz, Hannah R., McNitt, Sean M., Brenner, Michelle K., Boyer, Michael P., Addington, Adele K., Hutson, Susan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203766/
https://www.ncbi.nlm.nih.gov/pubmed/30318512
http://dx.doi.org/10.1038/s41416-018-0283-7