Cargando…
Mice deficient in the mitochondrial branched-chain aminotransferase (BCATm) respond with delayed tumour growth to a challenge with EL-4 lymphoma
BACKGROUND: The mitochondrial branched-chain aminotransferase (BCATm) is a recently discovered cancer marker with a poorly defined role in tumour progression. METHODS: To understand how a loss of function of BCATm affects cancer, the global knockout mouse BCATmKO was challenged with EL-4 lymphoma un...
Autores principales: | Ananieva, Elitsa A., Bostic, Joshua N., Torres, Ashley A., Glanz, Hannah R., McNitt, Sean M., Brenner, Michelle K., Boyer, Michael P., Addington, Adele K., Hutson, Susan M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203766/ https://www.ncbi.nlm.nih.gov/pubmed/30318512 http://dx.doi.org/10.1038/s41416-018-0283-7 |
Ejemplares similares
-
The emerging role of the branched chain aminotransferases, BCATc and BCATm, for anti-tumor T-cell immunity
por: Wetzel, Tanner J., et al.
Publicado: (2023) -
Branched-chain amino acid metabolism in cancer
por: Ananieva, Elitsa A., et al.
Publicado: (2018) -
Crosstalk between arginine, glutamine, and the branched chain amino acid metabolism in the tumor microenvironment
por: Wetzel, Tanner J., et al.
Publicado: (2023) -
Expression of mitochondrial branched-chain aminotransferase and α-keto-acid dehydrogenase in rat brain: implications for neurotransmitter metabolism
por: Cole, Jeffrey T., et al.
Publicado: (2012) -
Risk factors for ventricular tachyarrhythmic events in patients without left bundle branch block who receive cardiac resynchronization therapy
por: Younis, Arwa, et al.
Publicado: (2021)