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Oncogenic potential of BEX4 is conferred by Polo-like kinase 1-mediated phosphorylation
The brain-expressed X-linked 4 (BEX4) gene has been recently identified as a mediator of microtubule hyperacetylation through sirtuin 2 inhibition and is highly overexpressed in human cancers. However, the gain-of-function molecular mechanism of the BEX4 gene in human cancers still needs to be eluci...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203768/ https://www.ncbi.nlm.nih.gov/pubmed/30367032 http://dx.doi.org/10.1038/s12276-018-0168-0 |