The mitochondrial antioxidant SS-31 increases SIRT1 levels and ameliorates inflammation, oxidative stress and leukocyte-endothelium interactions in type 2 diabetes

There is growing focus on mitochondrial impairment and cardiovascular diseases (CVD) in type 2 diabetes (T2D), and the development of novel therapeutic strategies in this context. It is unknown whether mitochondrial-targeting antioxidants such as SS-31 protect sufficiently against oxidative damage i...

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Detalles Bibliográficos
Autores principales: Escribano-Lopez, Irene, Diaz-Morales, Noelia, Iannantuoni, Francesca, Lopez-Domenech, Sandra, de Marañon, Aranzazu M, Abad-Jimenez, Zaida, Bañuls, Celia, Rovira-Llopis, Susana, Herance, Jose R, Rocha, Milagros, Victor, Victor M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203778/
https://www.ncbi.nlm.nih.gov/pubmed/30367115
http://dx.doi.org/10.1038/s41598-018-34251-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203778/
https://www.ncbi.nlm.nih.gov/pubmed/30367115
http://dx.doi.org/10.1038/s41598-018-34251-8

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