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Mutual inhibition between PTEN and PIP3 generates bistability for polarity in motile cells
Phosphatidylinositol 3,4,5-trisphosphate (PIP3) and PIP3 phosphatase (PTEN) are enriched mutually exclusively on the anterior and posterior membranes of eukaryotic motile cells. However, the mechanism that causes this spatial separation between the two molecules is unknown. Here we develop a method...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203803/ https://www.ncbi.nlm.nih.gov/pubmed/30367048 http://dx.doi.org/10.1038/s41467-018-06856-0 |